A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Cortisol, Free and Cortisone, 24-Hour Urine with Creatinine
Test CodeCCF24
Alias/See Also
37355
CPT Codes
82530, 82542, 82570
Includes
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
2 mL of 24 hour urine collected in a 24-hour urine container, no preservative
Minimum Volume
0.5 mL
Other Acceptable Specimens
24 hour urine collected in a leak-proof urine container, with 25 mL 6N HCl, or 10 mL conc. glacial acetic acid, or 10 g Boric acid
Instructions
Collect urine with 10 grams of boric acid or keep urine refrigerated during collection if preservative is not used. Record 24-hour urine volume on test requisition and urine vial.
Reference ranges do not apply to random urine samples.
Reference ranges do not apply to random urine samples.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 90 days
Refrigerated: 21 days
Frozen: 90 days
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Fri; Report available: 2-6 days after receipt at the performing laboratory. Add three (3) days for transport.
Reference Range
Cortisol, Free, 24-Hr Urine
Cortisone, 24-Hr Urine
Creatinine, 24-Hour Urine
Adult | 4.0-50.0 mcg/24 hrs |
Pediatric | |
1-4 Years | 0.9-8.2 mcg/24 hrs |
5-9 Years: | 1.0-30.0 mcg/24 hrs |
10-13 Years | 1.0-45.0 mcg/24 hrs |
14-17 Years: | 3.0-55.0 mcg/24 hrs |
Cortisone, 24-Hr Urine
Adult | 23-195 mcg/24 hrs |
Creatinine, 24-Hour Urine
<3 Years | Not established | |
3-8 Years | 0.10-0.80 g/24 hours | |
9-12 Years | 0.20-1.40 g/24 hours | |
13-17 Years | 0.40-1.90 g/24 hours | |
>17 Years | 0.50-2.15 g/24 hours |
Clinical Significance
Urinary free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |
Last Updated: May 4, 2023