Resources

Acyclovir, Serum/Plasma

Test Code
ACYCL


Alias/See Also
901263


CPT Codes
80299

Preferred Specimen
1 mL serum collected in a red-top tube (no gel)


Minimum Volume
0.2 mL


Other Acceptable Specimens
Plasma collected in an EDTA (lavender-top), or (pink-top) tube


Instructions
Promptly centrifuge and separate serum or plasma into a plastic screw-cap vial.


Transport Container
Plastic screw-cap vial


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 4 months


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Polymer gel separation tube (SST or PST)


Methodology
High Performance Liquid Chromatography (HPLC)

Setup Schedule
Set up: Thurs; Report available: 8 days


Reference Range

<0.1 mcg/mL



Clinical Significance
Acyclovir is commonly used in the treatment of Herpes Simplex Virus (HSV). Measurement of serum drug levels may be helpful to optimize drug dosing regimens, particularly where there is non-compliance, concern about drug interactions, pharmacokinetic variability, or suspected toxicity.


Performing Laboratory
NMS Labs
200 Welsh Rd
Horsham, PA 19044


Last Updated: August 4, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.