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Acyclovir, Serum/Plasma
Test CodeACYCL
Alias/See Also
901263
CPT Codes
80299
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.2 mL
Other Acceptable Specimens
Plasma collected in an EDTA (lavender-top), or (pink-top) tube
Instructions
Promptly centrifuge and separate serum or plasma into a plastic screw-cap vial.
Transport Container
Plastic screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 4 months
Refrigerated: 30 days
Frozen: 4 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Polymer gel separation tube (SST or PST)
Methodology
High Performance Liquid Chromatography (HPLC)
Setup Schedule
Set up: Thurs; Report available: 8 days
Reference Range
<0.1 mcg/mL
Clinical Significance
Acyclovir is commonly used in the treatment of Herpes Simplex Virus (HSV). Measurement of serum drug levels may be helpful to optimize drug dosing regimens, particularly where there is non-compliance, concern about drug interactions, pharmacokinetic variability, or suspected toxicity.
Performing Laboratory
NMS Labs
200 Welsh Rd
Horsham, PA 19044
Last Updated: August 4, 2023