Resources

Arbovirus Antibodies (IgG, IgM), IFA, Serum

Test Code
ARBGM


Alias/See Also
34980


CPT Codes
86651 (x2), 86652 (x2), 86653 (x2), 86654 (x2)

Includes
California Encephalitis (IgG, IgM),  Eastern Equine Encephalitis (IgG, IgM), St. Louis Encephalitis (IgG, IgM), Western Equine Encephalitis (IgG, IgM)


Preferred Specimen
1 mL serum collected in a red-top tube (no gel)


Minimum Volume
0.2 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Icteric • Lipemic samples


Methodology
Immunofluorescence Assay (IFA)

Setup Schedule
Monday-Friday Morning Report available: 3 Days after receipt at the performing laboratory. Add three (3) days for transport.


Limitations
False-positive results may be produced if the patient has been immunized against yellow fever or if the patient has had previous infections that produce similar, cross-reacting antibodies.


Reference Range
See individual tests


Clinical Significance
Serum is tested against antigens of California Encephalitis (La Crosse), Eastern Equine Encephalitis, St. Louis Encephalitis and Western Equine Encephalitis viruses. IgG titers >=1:16 suggest exposure, while the presence of IgM indicates recent infection. Incidence is seasonal from mid- to late-summer (July-October).


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042



Last Updated: May 4, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.