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Echovirus Antibodies, Serum

Test Code
ECHA1


Alias/See Also
35139


CPT Codes
86658 (x5)

Includes
Echovirus serotypes 4, 7, 9, 11, and 30


Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Methodology
Complement Fixation (CF)

Setup Schedule
Set up: Tues-Sat; Report available: 1-5 days after receipt at the performing laboratory. Add three (3) days for transport.


Reference Range
Echovirus 4 Ab <1:8 titer
Echovirus 7 Ab <1:8 titer
Echovirus 9 Ab <1:8 titer
Echovirus 11 Ab <1:8 titer
Echovirus 30 Ab <1:8 titer

Interpretation Criteria
<1:8 Antibody Not Detected
≥1.8 Antibody Detected


Clinical Significance
The current echovirus panel includes serotypes 4, 7, 9, 11, and 30. The echovirus serotypes used in this panel will vary depending upon current epidemiological data available from inhouse isolations CDC reports. Generally, the serotypes used are those most commonly associated with viral meningitis. Although there is cross-reactivity among the enteroviruses, most healthy people do not have detectable CF titers (>1:8). Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042



Last Updated: June 22, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.