A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Collagen Cross-Linked N-Telopeptide (NTx), Urine
Test CodeNTXUR
Alias/See Also
36167
CPT Codes
82523, 82570
Includes
Creatinine
Preferred Specimen
2 mL urine from second morning void submitted in a leak-proof container, no preservative
Minimum Volume
1 mL
Other Acceptable Specimens
Random urine, catheterized, or first morning void clean catch, submitted in a leak-proof urine container, no preservative
Instructions
Do not use preservatives. Acidified specimen is not acceptable. Second morning void urine: Discard the first morning void. Collect the second morning void. Mix well.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 5 days
Frozen: 30 days
Refrigerated: 5 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Acidified specimen • Preserved specimen
Methodology
Chemiluminescence (CL)
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Report Available
Please allow an additional two (2) days for transport to the performing labortatory.
Reference Range
Collagen Cross-Linked N-Telopeptide (NTx), Random Urine
Results are primarily used for monitoring the response to therapy. A value within the premenopausal reference range does not rule out osteoporosis nor the need for therapy.
Creatinine, Random Urine
Male | |
18-29 Years | 12-99 nM BCE/mM creat |
30-59 Years | 9-60 nM BCE/mM creat |
Female | |
Premenopausal | 4-64 nM BCE/mM creat |
Creatinine, Random Urine
≤6 Months | 2-28 mg/dL |
7-11 Months | 2-31 mg/dL |
1-2 Years | 2-110 mg/dL |
3-8 Years | 2-130 mg/dL |
9-12 Years | 2-160 mg/dL |
>12 Years Male | 20-320 mg/dL |
>12 Years Female | 20-275 mg/dL |
Clinical Significance
NTx is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss. A decline of 30% or more of NTx over a six-month period suggests effective therapy.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: December 10, 2024