Beta-2-Microglobulin, Serum : 852

Test Code

B2MCGS or 852

CPT Codes
82232

Transport Container

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Transport Temperature

Room temperature.

Specimen Stability

Room temperature: 5 days; Refrigerated: 7 days; Frozen: 30 days

Methodology
Immunoturbidimetric

Setup Schedule

Sunday -Saturday

Report Available

1 day

Reference Range

<18 Years Not established
Adults < 2.52 mg/L

Clinical Significance

Beta-2-microglobulin normally passes through the glomerulus into the proximal tubule where much of it is reabsorbed. Serum levels are therefore an index of glomerular function. When impaired, serum levels rise in inverse ratio to glomerular filtration rate. Increased amounts of beta-2-microglobulin are excreted in several renal disorders, e.g., Balkan nephropathy, heavy metal poisoning and renal tubular disease due to therapeutic agents. Serial levels of beta-2-microglobulin in serum and urine are used to evaluate transplant viability and anticipate rejection. Following a successful graft, serum levels decline toward normal. Increasing serum levels provide an early sign of rejection. Elevated levels are also noted in lymphproliferative disorders, neoplasms (malignant and benign), inflammatory disease, and autoimmune diseases such as systemic lupus erythematosus (SLE) and Sjögren's disease.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.