Solid TumorSEQ Expanded Panel : 1017066

Test Code

MDFCPSTEP or 1017066

CPT Codes
0379U

Includes

see below link to gene chart
https://s7d6.scene7.com/is/image/questdiagnostics/FAQ273_Q4_Table_Gene_Content-1

Transport Container

Submit Paraffin embedded tissue (PET) block accompanied by a circled H & E slide indicating the area to be examined: submit in sterile biohazard plastic bag.

Slides: submit 10 x 10 µm PET slides (minimum 5 x 5 µm) and H & E slide in slide holder.

Specimen to be tested must contain a minimum of 10 percent tumor (20 percent preferred).

Transport Temperature

Paraffin embedded Tissue Block: Ambient or on ice pack in summer; Slides: Ambient.

Specimen Stability

Paraffin embedded tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Methodology
Next Generation Sequencing

Setup Schedule

Monday & Wednesday & Friday

Report Available

10-14 days

Reference Range

An interpretive report will be provided.

Clinical Significance

The 523-gene expanded panel is intended to help oncologists deliver precision medicine by providing personalized genomic analysis of a patient’s tumor. The expanded panel offers the opportunity for a broader scope of genomic information. For example, it may be useful for patients with limited or ill-defined treatment options and for those considering clinical trials. This panel uses next-generation sequencing to detect mutations present in DNA and RNA extracted from formalin-fixed, paraffin embedded (FFPE) tissue sections of solid tumors. The test is designed to detect single nucleotide variants (SNVs) and small insertions/deletions, as well as whole-gene copy number alterations and translocations in a select group of genes. Microsatellite instability (MSI) and tumor mutation burden (TMB) are also evaluated.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.