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Heparin, Anti-Xa : 30292
Test CodeHEPXA or 30292
CPT Codes
85520
Instructions
Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/uL). Freeze immediately and ship on dry ice.
Transport Container
Preferred Specimen
2 mL frozen plasma collected in 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1 mL
2 mL frozen plasma collected in 3.2% sodium citrate (light blue-top) tube
Minimum Volume
1 mL
Transport Temperature
Frozen.
Specimen Stability
Room temperature: Unacceptable; Refrigerated: Unacceptable; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis
Methodology
Chromogenic Assay
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
UFH Therapeutic Range 0.30-0.70 IU/mL
LMWH Therapeutic Ranges (target anti-Xa levels measured 4 hours after dosing):
Enoxaparin (Lovenox)
Therapeutic bid dosing 0.6-1.0 IU/mL
Therapeutic qD dosing >1.0 IU/mL
Tinzaparin (Innohep)
Therapeutic qD 0.85 IU/mL
Dalteparin (Fragmin)
Therapeutic qD 1.05 IU/mL
Clinical Significance
This assay is useful in measuring heparin concentration in patients treated with low molecular weight heparins (i.e. Enoxaparin/Lovenox) or unfractionated heparin. It is not intended for measurement of Rivaroxaban (Xarelto) or Fondaparinux (Arixtra).
Performing Laboratory
med fusion
