ACTH, Plasma : 211

Test Code
ACTHPL or 211

Alias/See Also
Corticotropin,Adrenocorticotropic Hormone

CPT Codes

Centrifuge immediately after collection to separate plasma from cells. Transfer plasma to a plastic specimen transport container and mark the specimen type as plasma on the container. Freeze immediately.
ACTH measurement is not recommended for patients who have been administered cosyntropin (ACTH (1-24)) because the results may be falsely elevated or depressed. Reference: Siemens Healthcare Customer Notification IMC20-04.A.US March 25, 2020.

Transport Container
Preferred Specimen
1.5 mL plasma collected in an EDTA (lavender-top) tube
Alternative Specimen
PPT-potassium EDTA (white-top) tube
Minimum Volume
0.5 mL
Collect specimen between 7 a.m. and 10 a.m. If drawn at any other time, the reference ranges do not apply.

Transport Temperature

Specimen Stability
Room temperature: 16 hours; Refrigerated: 24 hours; Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received thawed, Received room temperature, Received refrigerated


Setup Schedule
Sunday - Saturday

Report Available
1 day

Reference Range
<3 Years                Not established

3-17 Years             9-57 pg/mL

≥18 Years              6-50 pg/mL

Clinical Significance
Determination of ACTH is useful in differentiating between primary and secondary adrenocortical hypo- and hyperfunctional disorders: Addison's Disease, Cushing's Syndrome, Adrenal Carcinoma, Ectopic ACTH Syndrome, Nodular Hyperplasia.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.