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Creatinine, 24-Hour Urine : 381
Test Code24CRAU or 381
CPT Codes
82570
Instructions
Record total volume and collection time on specimen container and test requisition.
Transport Container
Preferred Specimen
10 mL urine aliquot from a well-mixed, 24-hour collection - no preservative
Alternative Specimens
Acidified urine; Urinalysis transport tube (yellow-top, blue fill line, preservative tube)
Minimum Volume
2 mL
10 mL urine aliquot from a well-mixed, 24-hour collection - no preservative
Alternative Specimens
Acidified urine; Urinalysis transport tube (yellow-top, blue fill line, preservative tube)
Minimum Volume
2 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 28 days
Methodology
Colorimetric; Kinetic
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
<3 Years Not established
3-8 Years 0.10-0.80 g/24 h
9-12 Years 0.20-1.40 g/24 h
13-17 Years 0.40-1.90 g/24 h
>17 Years 0.50-2.15 g/24 h
Clinical Significance
Creatinine is the endproduct of creatine metabolism. Creatine is present primarily in muscle and the amount of creatinine produced is related to total skeletal muscle mass. Daily creatinine production is fairly constant except when there is massive injury to muscle. The kidneys excrete creatinine very efficiently and blood levels and daily urinary excretion of creatinine fluctuates very little in healthy normal people. Since blood and daily urine excretion of creatinine shows minimal fluctuation, creatinine excretion is useful in determining whether 24-hour urine specimens for other analytes (e.g., protein) have been completely and accurately collected.
Performing Laboratory
med fusion