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Creatinine Clearance : 7943
Test CodeCRCLAU or 7943
CPT Codes
82575
Includes
Creatinine (serum and urine), Creatinine Clearance (calculation), eGFR
Instructions
Record total volume and collection duration on specimen container and test requisition. Indicate the patient's height (in feet and inches) and weight (in lbs.) on test requisition.
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Transport Container
Preferred Specimen
10 mL aliquot from a well-mixed, 24-hour urine collection - no preservative
and 1 mL serum
Alternative Specimens
Acidified urine ; Urinalysis transport tube (yellow-top, blue fill line, preservative tube; Serum collected in: Spun Serum Separator Tube (SST®) or Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Minimum Volume
0.5 mL urine; 0.5 mL serum
10 mL aliquot from a well-mixed, 24-hour urine collection - no preservative
and 1 mL serum
Alternative Specimens
Acidified urine ; Urinalysis transport tube (yellow-top, blue fill line, preservative tube; Serum collected in: Spun Serum Separator Tube (SST®) or Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Minimum Volume
0.5 mL urine; 0.5 mL serum
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly icteric serum
Methodology
Spectrophotometry
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
Creatinine
Age Male (mg/dL) Female (mg/dL)
≤2 days 0.79-1.58 0.79-1.58
3-27 days 0.35-1.23 0.35-1.23
1 month-9 years 0.20-0.73 0.20-0.73
10-12 years 0.30-0.78 0.30-0.78
13-15 years 0.40-1.05 0.40-1.00
16-17 years 0.60-1.20 0.50-1.00
18-29 years 0.60-1.24 0.50-0.96
30-39 years 0.60-1.26 0.50-0.97
40-49 years 0.60-1.29 0.50-0.99
50-59 years 0.70-1.30 0.50-1.03
60-69 years 0.70-1.35 0.50-1.05
70-79 years 0.70-1.28 0.60-1.00
≥80 years 0.70-1.22 0.60-0.95
For patients >49 years of age, the upper reference limit for creatinine is approximately 13% higher for people identified as African-American.
eGFR ≥60 mL/min/1.73m2
Creatinine, 24-Hour Urine
<3 Years Not established
3-8 Years 0.10-0.80 g/24 h
9-12 Years 0.20-1.40 g/24 h
13-17 Years 0.40-1.90 g/24 h
>17 Years 0.50-2.15 g/24 h
Creatinine Clearance, Urine
Male 85-125 mL/min
Female 75-115 mL/min
Clinical Significance
Creatinine Clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant except when there is massive injury to muscle.
Performing Laboratory
med fusion
