Lymphocyte Subset Panel 5 : 8360

Test Code
CD4PF or 8360

Alias/See Also

CPT Codes

 % CD4, Absolute CD4+ Cells, Absolute Lymphocytes

Transport Container
Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume
0.5 mL

Transport Temperature
Room temperature.

Specimen Stability
Room temperature: 72 hours; Refrigerated: Unacceptable; Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis; Lithium heparin (green-top) tube; ACD (yellow-top) tube; Clotted

Flow Cytometry

Setup Schedule
Tuesday - Saturday

Report Available
2-4 days

Reference Range
See Laboratory Report

Clinical Significance
A significant reduction in CD4 count can lead to opportunistic infections, and the CD4 cell count/percentage can he used to make decisions regarding opportunistic infection prophylaxis as per guidelines.
During the first 2 years of antiretroviral (ARV) therapy, CD4 levels should be tested every 3 to 6 months. Patients who develop viremia while on therapy or whose CD4 count stays below 300 cells/µL should also have their CD4 levels tested every 3 to 6 months. After 2 years of ARV therapy, with consistently suppressed viral load and a CD4 count of 300 to 500 cells/µL, CD4 counts should be tested every 12 months. Note that when CD4 counts are > 500 cells/ µL, CD4 testing is optional. CD4 testing should also be conducted if therapy fails. Refer to current HIV management guidelines for further information on recommended testing frequency.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.