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Lymphocyte Subset Panel 5 : 8360
Test CodeCD4PF or 8360
Alias/See Also
Flow
CPT Codes
86361
Includes
% CD4, Absolute CD4+ Cells, Absolute Lymphocytes
Transport Container
Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
5 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 72 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis; Lithium heparin (green-top) tube; ACD (yellow-top) tube; Clotted
Methodology
Flow Cytometry
Setup Schedule
Tuesday - Saturday
Report Available
2-4 days
Reference Range
See Laboratory Report
Clinical Significance
A significant reduction in CD4 count can lead to opportunistic infections, and the CD4 cell count/percentage can he used to make decisions regarding opportunistic infection prophylaxis as per guidelines.
During the first 2 years of antiretroviral (ARV) therapy, CD4 levels should be tested every 3 to 6 months. Patients who develop viremia while on therapy or whose CD4 count stays below 300 cells/µL should also have their CD4 levels tested every 3 to 6 months. After 2 years of ARV therapy, with consistently suppressed viral load and a CD4 count of 300 to 500 cells/µL, CD4 counts should be tested every 12 months. Note that when CD4 counts are > 500 cells/ µL, CD4 testing is optional. CD4 testing should also be conducted if therapy fails. Refer to current HIV management guidelines for further information on recommended testing frequency.
During the first 2 years of antiretroviral (ARV) therapy, CD4 levels should be tested every 3 to 6 months. Patients who develop viremia while on therapy or whose CD4 count stays below 300 cells/µL should also have their CD4 levels tested every 3 to 6 months. After 2 years of ARV therapy, with consistently suppressed viral load and a CD4 count of 300 to 500 cells/µL, CD4 counts should be tested every 12 months. Note that when CD4 counts are > 500 cells/ µL, CD4 testing is optional. CD4 testing should also be conducted if therapy fails. Refer to current HIV management guidelines for further information on recommended testing frequency.
Performing Laboratory
Quest Diagnostics
