Lymphocyte Subset Panel 3 : 7195

Please submit a copy of the most recent CBC with differential report and any clinical information related to the patient's disease state. The CBC w/diff is needed for the reporting of the flow cytometry interpretative results.

TCELLF or 7195

CD3 (T-cell Panel); CD4 (T-cell Panel); CD8 (T-cell Panel); CD4/CD8 ratio (T-cell Panel); T-cell Panel; Immunophenotyping (T-cell Panel) 

Panel includes: CD3, CD4, CD8 and CD4/CD8 ratio, and Absolute Lymphocytes

Peripheral blood in a lavender top (EDTA) tube (4-10 mL). 

The specimen must be received within 36 hours of collection. Do not centrifuge.

Room temperature within 36 hours.

Lavender (EDTA):  Room temperature: 36 hours; Refrigerated: Unacceptable;  Frozen: Unacceptable

<85% Viability for Lymphocytic Subset panels; Centrifuged specimens.

Sunday - Saturday

1-2 days

Laboratory test results should always be considered in the context of clinical observations. This test was developed and its performance characteristics determined by med fusion. It has not been cleared or approved by the U.S. Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary. This test is used for clinical purposes. It should not be regarded as investigational for research. This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) as qualified to perform high complexity clinical laboratory testing.

Age                  C3 Absolute  CD3 Percentage (%)
0-3 Months     2500-5500      53- 84
3-6 Months     2500-5600      51-77
6-12 Months    1900-5900       49-76
1-2 Years         2100-6200      53-75
2-6 Years         1400-3700      56-75
6-12 Years        1200-2600      60-76
12-18 years       1000-2200      56-84
Adult                 840-3060        57-85

Age                CD4 Absolute   CD4 Percentage (%)
0-3 Months    1600-4000          35-64
3-6 Months    1800-4000          35-56
6-12 Months   1400-4300          31-56
1-2 Years        1300-3400          32-51
2-6 Years       700-2200           16-30
6-12 Years       650-1500           31-47
12-18 years      530-13000            31-52
Adult               490-1740              30-61

Age                 CD8 Absolute    CD8 Percentage (%)
0-3 Months     560-1700             12-28
3-6 Months     590-1600             12-23
6-12 Months    500-1700             12-24
1-2 Years         620-2000             14-30
2-6 Years        490-1300              16-30
6-12 Years       370-1100               18-35 
12-18 years       330-920               18-35
Adult                180-1170               12-42    
      
Age                  CD4:8 Ratio
0-3 Months      2.1-12.5
3-6 Months       2.1-12.5
6-12 Months      0.6-5.3
1-2 Years           0.6-5.3
2-6 Years          1.4-3.4
6-12 Years         1.0-3.3
12-18 years         0.6-3.9
Adult                  0.86-5.00

Absolute Lymphocytes     850-3900 cells/uL

The measurement of lymphocyte subsets may be useful in monitoring immunosuppressive therapies and determining the immune status of patients. These quantitative tests are measured out in absolute numbers which are determined from different cell types such as total T-cells, CD4 T-cells, CD8 T-cells, B-cells, and NK cells.  For example, CD4 counts are commonly used for monitoring HIV infected patients