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Neurokinin A (Substance K) : 17089
Test CodeNEUROQ or 17089
CPT Codes
83519
Instructions
Patient should not be on any medications that affect hypertension, gastrointestinal functions or pain relievers, if possible for at least 48 hours prior to collection of specimen.
Collect 10 mL blood directly into ISI's Z-tube™ Preservative and separate as soon as possible. Freeze plasma immediately after separation.
Collect 10 mL blood directly into ISI's Z-tube™ Preservative and separate as soon as possible. Freeze plasma immediately after separation.
Transport Container
Specimen
3 mL frozen plasma collected in a 10 mL InterScience Institute’s (ISI) Z-tube™ Preservative
3 mL frozen plasma collected in a 10 mL InterScience Institute’s (ISI) Z-tube™ Preservative
Transport Temperature
Frozen.
Specimen Stability
Room temperature: Unacceptable; Refrigerated: Unacceptable; Frozen: Acceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature; Received refrigerated; Not collected in a Z-tube™
Methodology
Direct Radioimmunoassay
Setup Schedule
Varies
Report Available
7 days (From receipt at performing laboratory)
Limitations
This test was developed and its performance characteristics have been determined by Inter Science Institute. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
Reference Range
Up to 40 pg/mL
Clinical Significance
Neurokinin A is a ten amino acid putative transmitter synthesized in the neurons it is present in. Neurokinin A is a member of the family called Tachykinins which also include Neurokinin B, Substance P, Physalaemin, and Eledoisin. Neurokinin A shares 6 of 10 peptide homologies with Neurokinin B even though they are produced by different genes. Neurokinin A is also very similar in structure to Substance P and produces some of the same biological actions as Substance P. Neurokinin A is a potent bronchoconstrictor. In the gut, Neurokinin A is produced by the intrinsic enteric nervous system.
Performing Laboratory
Interscience Institute