Lipid Panel with Reflex to Direct LDL : 14852

Test Code
LIPRAU or 14852

Alias/See Also
Non-fasting Lipid Panel with Reflex

CPT Codes

Cholesterol, Total; Triglycerides; HDL Cholesterol; LDL-Cholesterol (calculated); Cholesterol/HDL Ratio (calculated); Non-HDL Cholesterol (calculated); If Triglyceride result is >400 mg/dL, then Direct LDL will be performed at an additional charge (CPT code(s): 83721). (If reflex: 8293 LDLAU)

Fasting is not required prior to collection of a lipid panel.
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.

Transport Container
Preferred Specimen
2 mL serum
Alternative Specimens
Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Collection Instructions:
Centrifuge within 30-60 minutes following collection

Transport Temperature
Room temperature.

Specimen Stability
Room temperature: 48 hours; Refrigerated: 7 days; Frozen: 28 days
Room temperature: 48 hours; Refrigerated: 48 hours; Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Moderate to gross icterus. Anticoagulants other than heparin

Spectrophotometry; if reflex. Enzymatic

Setup Schedule
Sunday - Saturday

Report Available
1 day

Reference Range
                                      Male      Female


Total Cholesterol

<20 Years                      <170      <170

≥20 Years <200 <200

HDL Cholesterol  

<20 Years                        >45        >45

≥20 Years ≥40 ≥50


≤9 Years <75 <75

10-19 Years <90 <90

≥20 Years <150 <150  

LDL-Cholesterol (calc)  

<20 Years <110 <110

≥20 Years <100 <100

Cholesterol/HDL Ratio (calc) <5.0 <5.0

Non-HDL Cholesterol (calc)  

<20 Years <120 <120

≥20 Years <130 <130


If  reflex: 


<20 Years <110 mg/dL

≥20 Years <100 mg/dL

Clinical Significance
The Lipid Panel with Reflex to Direct LDL panel includes evaluation of total cholesterol, HDL-cholesterol, triglyceride (TG), LDL-cholesterol (calculated), cholesterol/HDL ratio (calculated), and non-HDL cholesterol; direct LDL-C measurement will be performed at additional cost if the TG level is >400 mg/dL. This panel is useful in the detection, classification, and monitoring of hyperlipidemia, especially those expected to have highly elevated TG levels.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.