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Lipid Panel, Standard : 7600
Test CodeLIPDAU or 7600
Alias/See Also
Standard Lipid Panel, Martin Hopkins calculation, Non-fasting Lipid Panel
CPT Codes
80061
Includes
Cholesterol, Total; Triglycerides; HDL Cholesterol; LDL-Cholesterol (calculated); Cholesterol/HDL Ratio (calculated); Non-HDL Cholesterol (calculated)
Instructions
Fasting is not required prior to collection of a lipid panel.
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.
Transport Container
Preferred Specimen
1 mL serum
Alternative Specimens
Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Minimum Volume
0.5 mL
Collection Instructions:
Centrifuge within 30-60 minutes following collection
1 mL serum
Alternative Specimens
Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Minimum Volume
0.5 mL
Collection Instructions:
Centrifuge within 30-60 minutes following collection
Transport Temperature
Room temperature.
Specimen Stability
Serum
Room temperature: 48 hours; Refrigerated: 7 days; Frozen: 28 days
Plasma
Room temperature: 48 hours; Refrigerated: 48 hours; Frozen: 28 days
Room temperature: 48 hours; Refrigerated: 7 days; Frozen: 28 days
Plasma
Room temperature: 48 hours; Refrigerated: 48 hours; Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Moderate to gross icterus. Anticoagulants other than heparin
Methodology
Spectrophotometry
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
Male Female
(mg/dL)
Total Cholesterol
<20 Years <170 <170
≥20 Years <200 <200
HDL Cholesterol
<20 Years >45 >45
≥20 Years ≥40 ≥50
Triglycerides
≤9 Years <75 <75
10-19 Years <90 <90
≥20 Years <150 <150
LDL-Cholesterol (calc)
<20 Years <110 <110
≥20 Years <100 <100
Cholesterol/HDL Ratio (calc) <5.0 <5.0
Non-HDL Cholesterol (calc)
<20 Years <120 <120
≥20 Years <130 <130
Clinical Significance
The Lipid Panel, Standard measures serum cholesterol and triglyceride (TG) levels; it includes evaluation of the cholesterol/HDL-C ratio (calculated), HDL-C, LDL-C (calculated), non-HDL-C (calculated), total cholesterol, and TG. Comprehensive lipid assessment aids in the evaluation of cardiovascular risk and the likelihood of suffering an ischemic event. It is also useful for the prevention and management of atherosclerotic disease, as well as the diagnosis of metabolic syndrome [1].
Cardiovascular disease (CVD) is the leading cause of death in the United States. The risk of developing CVD and having an ischemic event is significantly increased in individuals with high LDL-cholesterol (LDL-C) and TG levels [2,3]. The American Heart Association (AHA) recommends that Americans aged 20 and above have their lipid levels tested every 4 to 6 years. Children should have their cholesterol tested for the first time between ages 9 and 11, and again between ages 17 and 21. Testing should start earlier if there is family history of high cholesterol [4].
The AHA recommends repeat measurement of LDL-C within 4 to 12 weeks of starting or changing lipid-lowering therapy, to assess response and adherence, and then every 3 to 12 months as appropriate [4].
Treatment with N-acetyl cysteine (NAC) for acetaminophen overdose may generate a falsely low result for cholesterol. Venipuncture immediately after or during administration of the painkiller metamizole (dipyrone) may also lead to falsely low results for cholesterol.
Note: Any or all individual tests from a panel can be ordered separately.
Cardiovascular disease (CVD) is the leading cause of death in the United States. The risk of developing CVD and having an ischemic event is significantly increased in individuals with high LDL-cholesterol (LDL-C) and TG levels [2,3]. The American Heart Association (AHA) recommends that Americans aged 20 and above have their lipid levels tested every 4 to 6 years. Children should have their cholesterol tested for the first time between ages 9 and 11, and again between ages 17 and 21. Testing should start earlier if there is family history of high cholesterol [4].
The AHA recommends repeat measurement of LDL-C within 4 to 12 weeks of starting or changing lipid-lowering therapy, to assess response and adherence, and then every 3 to 12 months as appropriate [4].
Treatment with N-acetyl cysteine (NAC) for acetaminophen overdose may generate a falsely low result for cholesterol. Venipuncture immediately after or during administration of the painkiller metamizole (dipyrone) may also lead to falsely low results for cholesterol.
Note: Any or all individual tests from a panel can be ordered separately.
Performing Laboratory
med fusion
