Iron, Total and Total Iron Binding Capacity : 7573

Test Code

FETIAU or 7573

CPT Codes
83540, 83550

Includes

Iron, Total, Iron Binding Capacity, % Saturation (calculated)

Instructions

Samples should be taken in the morning from patients in a fasting state, since iron values decrease by 30% during the course of the day and there can be significant interference from lipemia.

Transport Container

Preferred Specimen
1 mL serum

Alternative Specimens
Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube

Minimum Volume
0.5 mL

Transport Temperature

Room temperature.

Specimen Stability

Room temperature: 6 days; Refrigerated: 7 days; Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis, Anticoagulants other than heparin

Methodology
Spectrophotometry

Setup Schedule

Sunday - Saturday

Report Available

1 day

Reference Range

Iron, Total

Age Male Female

(mcg/dL)

<1 Month 32-112 29-127

1-11 Months 27-109 25-126

1-3 Years 29-91 25-101

4-19 Years 27-164 27-164

20-29 Years 50-195 40-190

30-49 Years 50-180 40-190

≥50 Years 50-180 45-160

Iron Binding Capacity

Age Male Female

mcg/dL (calc)

<1 Month 94-232 94-236

1-5 Months 116-322 89-311

6-11 Months 176-384 138-365

1-19 Years 271-448 271-448

≥20 Years 250-425 250-450

% Saturation

Age Male Female

% (calc)

<1 Year 10-48 12-45

1-12 Years 12-48 13-45

13-19 Years 16-48 15-45

≥20 Years 20-48 16-45

Clinical Significance

Serum iron quantification is useful in confirming the diagnosis of iron-deficiency anemia or hemochromatosis. The measurement of total iron binding in the same specimen may facilitate the clinician's ability to distinguish between low serum iron levels caused by iron deficiency from those related to inflammatory neoplastic disorders. The assay for iron measures the amount of iron which is bound to transferrin. The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferrin concentrations but expressed as an iron measurement. To obtain the percent saturation, the serum iron is divided by the TIBC which gives the actual amount of saturated transferrin. The percent saturation is low in iron deficiency and high in iron storage diseases.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.