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Direct LDL : 8293
Test CodeLDLAU or 8293
Alias/See Also
LDL Direct, Low Density Lipoprotein, DLDL ,LDL Cholesterol, Direct,Cholesterol, LDL
CPT Codes
83721
Instructions
If a Direct LDL-cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the Direct LDL cholesterol is ordered along with a lipid panel, then a fasting sample is not required.
Transport Container
Preferred Specimen
1 mL serum
Alternative Specimens
Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Minimum Volume
0.5 mL
1 mL serum
Alternative Specimens
Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Minimum Volume
0.5 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 6 days; Refrigerated: 7 days; Frozen: 31 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Anticoagulants other than heparin
Methodology
Enzymatic
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
<20 Years <110 mg/dL
≥20 Years <100 mg/dL
Clinical Significance
LDL cholesterol is a key factor in the pathogenesis of atherosclerosis and Coronary Artery Disease (CAD), while HDL cholesterol has often been observed to have a protective effect. Even within the normal range of total cholesterol concentrations, an increase in LDL cholesterol can produce an associated increased risk for CAD. LDL cholesterol binds to receptor sites on macrophages in blood vessel walls inciting several changes to the blood wall which enhance atherosclerotic plaque development.
Performing Laboratory
med fusion