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Dexamethasone Suppression Test (DST), 1 Specimen : 6921
Test CodeDST1SP or 6921
Alias/See Also
Cortisol Suppression
CPT Codes
82533
Instructions
The ordering physician should administer 1 mg Dexamethasone between 11:00 p.m. and midnight. Draw serum for cortisol testing between 7:00-9:00 a.m. the next morning. Mark tube with time and date drawn.
Note: Dexamethasone not supplied by the laboratory.
Note: Dexamethasone not supplied by the laboratory.
Transport Container
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
1 mL serum
Minimum Volume
0.5 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Monday - Saturday
Report Available
3 days (From receipt at performing laboratory)
Reference Range
8 A.M. Specimen
<2.0 mcg/dL Normal response
2.0-10.0 mcg/dL Equivocal
>10.0 mcg/dL High probability of Cushing's syndrome
Further diagnostic tests must be performed to confirm the diagnosis and determine etiology. Values >2.0 mcg/dL can be seen in endogenous depression and pseudo-Cushing's (alcoholism).
Clinical Significance
Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (Adrenal insufficiency).
Performing Laboratory
Quest Diagnostics
