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Complement Component C3c and C4c : 5704
Test CodeC3C4Q or 5704
Alias/See Also
C4 & C3 Complements
CPT Codes
86160x2
Includes
C3 and C4 complements
Transport Container
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
1 mL serum
Minimum Volume
0.5 mL
Transport Temperature
Refrigerated.
Specimen Stability
Room temperature: Unacceptable; Refrigerated: 4 days; Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature.
Methodology
Immunoturbidimetric
Setup Schedule
Sunday - Friday
Report Available
2-4 days (From receipt at performing Laboratory)
Reference Range
Complement C3
Male Female
<1 Year Not established Not established
1-14 Years 80-170 mg/dL 82-173 mg/dL
15-80 Years 82-185 mg/dL 83-193 mg/dL
≥81 Years Not established Not established
Complement C4
Male Female
<1 Year Not established Not established
1-14 Years 14-44 mg/dL 14-46 mg/dL
15-80 Years 15-53 mg/dL 15-57 mg/dL
≥81 Years Not established Not established
Male Female
<1 Year Not established Not established
1-14 Years 80-170 mg/dL 82-173 mg/dL
15-80 Years 82-185 mg/dL 83-193 mg/dL
≥81 Years Not established Not established
Complement C4
Male Female
<1 Year Not established Not established
1-14 Years 14-44 mg/dL 14-46 mg/dL
15-80 Years 15-53 mg/dL 15-57 mg/dL
≥81 Years Not established Not established
Clinical Significance
Decreased concentrations of both C3 and C4 suggest activation of the classical pathway, whereas decreased concentration of just C3 suggests activation of the alternative pathway. Both complement factors may be used to monitor activity of patients with systemic lupus erythematosus (SLE) and immune complex-induced vasculitis.
Performing Laboratory
Quest Diagnostics
