Alpha-1-Antitrypsin Quantitation : 235

Test Code
A1ATQ or 235


CPT Codes
82103

Transport Container
Allow blood to clot in the original closed container at room temperature (usually 20 to 30 minutes). After clot has formed, centrifuge blood 10 minutes at a relative centrifugal force (CRF) of 850 to 1000 g in the stoppered container.

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL


Transport Temperature
Refrigerated.


Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 90 days


Methodology
Immunoturbidimetric Assay

Setup Schedule
Tuesday & Thursday & Saturday


Report Available
2-4 days (From receipt at performing Laboratory)


Reference Range
83-199 mg/dL


Clinical Significance
Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, AAT phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.


Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.