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Alpha-1-Antitrypsin Quantitation : 235
Test CodeA1ATQ or 235
CPT Codes
82103
Transport Container
Allow blood to clot in the original closed container at room temperature (usually 20 to 30 minutes). After clot has formed, centrifuge blood 10 minutes at a relative centrifugal force (CRF) of 850 to 1000 g in the stoppered container.
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Transport Temperature
Refrigerated.
Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 90 days
Methodology
Immunoturbidimetric Assay
Setup Schedule
Tuesday & Thursday & Saturday
Report Available
2-4 days (From receipt at performing Laboratory)
Reference Range
83-199 mg/dL
Clinical Significance
Antitrypsin level may be increased in normal pregnancy and in several diseases including chronic pulmonary disease; hereditary angioedema; renal, gastric, liver and pancreatic diseases; diabetes; carcinomas and rheumatoid diseases. Alpha-1-Antitrypsin may be decreased in emphysema, hepatic cirrhosis, respiratory distress syndrome of the newborn, nephrosis, malnutrition and cachexia. If a deficiency is present, AAT phenotyping may be considered to confirm heterozygous versus homozygous deficiencies.
Performing Laboratory
Quest Diagnostics