Immunoglobulin G Subclasses Panel: 7903

Test Code
IMGSUB or 7903

CPT Codes
82784, 82787x4

Immunoglobulin G Subclasses 1, 2, 3, 4 and IgG (Immunoglobulin G)

Transport Container
Preferred Specimen 
2 mL serum
Minimum Volume
1 mL

Transport Temperature

Specimen Stability
Room temperature: 72 hours; Refrigerated: 10 days; Frozen: 30 days


Setup Schedule
Monday & Wednesday & Friday

Report Available
1-4 days

Reference Range
Age specific - See Laboratory Report 

Clinical Significance
In normal adults, IgG constitutes approximately 75% of the total serum immunoglobulin. Within the IgG class, the usual order of concentration of the 4 subclasses is IgG1>IgG2>IgG3>IgG4, but the actual concentration of each may vary markedly between individuals. The four IgG subclasses show considerable differences in their properties, including ability to fix complement, to bind to macrophages and to pass through the placenta. Abnormal levels of one or more subclass may be associated with certain conditions, including anaphylaxis, autoimmune- and gut diseases as well as hypo- and hyper-gammaglobulinaemia. Measurement of this immunoglobulin is an aid in the diagnosis of abnormal protein metabolism and the body’s lack of ability to resist infectious agents. This test should be used in conjunction with other laboratory and clinical findings.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.