Cortisol, Total  : 367

Test Code
CORTC or 367


Alias/See Also
Hydrocortisone, Total Cortisol, Cortisol, Serum


CPT Codes
82533

Instructions
  • Collect blood in gold top gel barrier or plain red top tube. Allow blood to clot and centrifuge to separate serum
  • Required serum volume: 1 mL (minimum 0.5 mL)
  • It is recommended to collect specimens between 7AM to 9AM, and/or 3PM to 5PM since cortisol levels follow a diurnal pattern in healthy individuals.
Assay not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay.


Transport Container
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL


Transport Temperature
Room temperature.


Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 28 days


Methodology
Immunoassay

Setup Schedule
Sunday - Saturday


Report Available
1 day


Reference Range
0-3 Days (infants)  


  Premature (31-35 Weeks)                 a.m. or p.m. ≤15.0 mcg/dL


  Term                                                   a.m. or p.m. ≤14.0 mcg/dL


4 Days-1 Month                                   a.m. or p.m. Not established


2-11 Months                                         a.m. 3.0-23.0 mcg/dL; p.m. Not established


1-17 Years                                            a.m. 3.0-25.0 mcg/dL; p.m. 3.0-17.0 mcg/dL


Adult 8 a.m. (7-9 a.m.) specimen        4.0-22.0 mcg/dL


Adult 4 p.m. (3-5 p.m.) specimen        3.0-17.0 mcg/dL



Clinical Significance
Cortisol is the primary glucocorticoid hormone synthesized and secreted by the adrenal cortex. Cortisol is increased in Cushing disease and decreased in Addison's disease.


Performing Laboratory
med fusion



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.