Phosphatidylserine/Prothrombin (PS/PT) Antibody (IgM) : 11446

Test Code
PSPTM or 11446

Alias/See Also

CPT Codes

Transport Container
Preferred Specimen
0.5 mL Citrated plasma collected from a 3.2% sodium citrate (light blue top) tube

Alternate  Specimen

Transport Temperature
Room temperature.

Specimen Stability
Room temperature: 7 days: Refrigerated: 30 days; Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, gross lipemia


Setup Schedule
Monday & Wednesday & Friday

Report Available
1-4 days

Reference Range
 ≤ 30 Units

Clinical Significance
Antiphospholipid Syndrome (APS) is an acquired autoimmune thrombophilia characterized by thrombosis (venous and/or arterial or microvascular) and/or pregnancy loss or morbidity in association with persistent positivity of a heterogeneous group of autoantibodies known as anti-phospholipid antibodies (APL). The international laboratory consensus criteria for the diagnosis of APS includes a positive lupus anticoagulant and/or moderate to high positivity for IgG/IgM Cardiolipin and Beta-2-Glycoprotein I antibodies. Although not included in the criteria classification for APS diagnosis, antibodies directed against a phosphatidylserine/prothrombin complex (PS/PT) have been reported to have a high association with venous thrombosis and obstetric abnormalities, but not with arterial thrombosis. In addition, a very high degree of concordance between the concentration of aPS/PT and lupus anticoagulant activity has been demonstrated.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.