Lyme Disease Antibody with Reflex to Blot (IgG, IgM) : 6646

Test Code
LYMABQ : 6646

Alias/See Also
Borrelia burgdorferi

CPT Codes

If Lyme Disease Antibody Screen is ≥0.90, then Lyme Disease Antibodies (IgG, IgM), Immunoblot will be performed at an additional charge (CPT code(s): 86617 x2 code LYMWBQ  IC 8593 ).

Transport Container
1 mL serum
Minimum Volume  0.7 mL

Transport Temperature
Room temperature.

Specimen Stability
Room Temperature: 7 days; Refrigerated: 14 days; Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, Grossly lipemic, Grossly icteric


Setup Schedule
Sunday, Tuesday - Saturday

Report Available
1-3 days (From receipt at performing laboratory)

Reference Range
Index        Interpretation 
<0.90          Negative 
0.90-1.09    Equivocal 
>1.09          Positive 
As recommended by the Food and Drug Administration (FDA), all samples with positive or equivocal results in a Borrelia burgdorferi antibody screen will be tested using a blot method. Positive or equivocal screening test results should not be interpreted as truly positive until verified as such using a supplemental assay (e.g., B. burgdorferi blot). 
The screening test and/or blot for B. burgdorferi antibodies may be falsely negative in early stages of Lyme disease, including the period when erythema migrans is apparent.

Clinical Significance
Lyme disease is caused by a bacterium borrelia burgdorferi and is transmitted by ticks. A screening test with high sensitivity is used as the first step in the CDC recommended algorithm. Immunoblot testing qualitatively examines, with high specificity, antibodies in a patient's specimen. Immunoblot testing is appropriate for confirming a detected screening result.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.