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Cardiolipin Antibodies (IgG, IgM) : 36333
Test CodeCLGMB or 36333
CPT Codes
86147x2
Includes
Panel includes: IgG and IgM antibodies.
Transport Container
Preferred Specimen:
1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube
Alternative Specimen:
Serum
Minimum Volume
0.5 mL
1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube
Alternative Specimen:
Serum
Minimum Volume
0.5 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 5 days; Refrigerated: 14 days; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, Grossly lipemic
Methodology
Immunoassay
Setup Schedule
Monday & Wednesday & Friday
Report Available
1-4 days
Reference Range
Cardiolipin Antibody (IgG)
<20.0 GPL-U/mL Antibody not detected
≥20.0 GPL-U/mL Antibody detected
Cardiolipin Antibody (IgM)
<20.0 MPL-U/mL Antibody not detected
≥20.0 MPL-U/mL Antibody detected
Clinical Significance
Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.
Performing Laboratory
med fusion
