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Progesterone : 745
Test CodePROGC or 745
CPT Codes
84144
Instructions
DHEA supplementation causes a false elevation of values in this standard Immunoassay method for progesterone. Physicians using progesterone levels as a criterion for triggering ovulation in an IVF cycle in patients supplemented with DHEA should assess progesterone levels using a LC/MS/MS progesterone assay.
Transport Container
Specimen:
1 mL serum
Minimum Volume: 0.5 mL
Note: Do not add on progesterone testing to a barrier gel specimen older than 72 hours.
1 mL serum
Minimum Volume: 0.5 mL
Note: Do not add on progesterone testing to a barrier gel specimen older than 72 hours.
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 72 hours; Refrigerated: 7 days; Frozen: 28 days
Do not add on Progesterone testing to a barrier gel specimen older than 72 hours.
Do not add on Progesterone testing to a barrier gel specimen older than 72 hours.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum stored on barrier gel for more than 72 hours
Methodology
Immunoassay
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
Female
Follicular Phase <1.0 ng/mL
Luteal Phase 2.6-21.5 ng/mL
Postmenopausal <0.5 ng/mL
Pregnancy
First Trimester 4.1-34.0 ng/mL
Second Trimester 24.0-76.0 ng/mL
Third Trimester 52.0-302.0 ng/mL
Children (<18 years old): Progesterone reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, a LC/MS/MS progesterone is recommended.
Follicular Phase <1.0 ng/mL
Luteal Phase 2.6-21.5 ng/mL
Postmenopausal <0.5 ng/mL
Pregnancy
First Trimester 4.1-34.0 ng/mL
Second Trimester 24.0-76.0 ng/mL
Third Trimester 52.0-302.0 ng/mL
Children (<18 years old): Progesterone reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, a LC/MS/MS progesterone is recommended.
Clinical Significance
Clinical evaluation of progesterone confirms ovulation and normal luteal function in nonpregnant women. Inadequate progesterone production by the corpus luteum may indicate luteal phase deficiency (LPD), which is associated with infertility and early miscarriage. Women using oral contraceptives have suppressed progesterone levels. Levels increase sharply during the luteal phase of the menstrual cycle. The level increases from 9 to 32 weeks of pregnancy.
Performing Laboratory
med fusion
