Progesterone : 745

Test Code
PROGC or 745

CPT Codes

DHEA supplementation causes a false elevation of values in this standard Immunoassay method for progesterone. Physicians using progesterone levels as a criterion for triggering ovulation in an IVF cycle in patients supplemented with DHEA should assess progesterone levels using a LC/MS/MS progesterone assay.

Transport Container
1 mL serum
Minimum Volume: 0.5 mL
Note: Do not add on progesterone testing to a barrier gel specimen older than 72 hours.

Transport Temperature
Room temperature.

Specimen Stability
Room temperature: 72 hours; Refrigerated: 7 days; Frozen: 28 days
Do not add on Progesterone testing to a barrier gel specimen older than 72 hours.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum stored on barrier gel for more than 72 hours


Setup Schedule
Sunday - Saturday

Report Available
1 day

Reference Range
  Follicular Phase <1.0 ng/mL 
  Luteal Phase 2.6-21.5 ng/mL 
  Postmenopausal  <0.5 ng/mL 
  First Trimester 4.1-34.0 ng/mL 
  Second Trimester 24.0-76.0 ng/mL 
  Third Trimester 52.0-302.0 ng/mL 
Children (<18 years old): Progesterone reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, a LC/MS/MS progesterone is recommended.

Clinical Significance
Clinical evaluation of progesterone confirms ovulation and normal luteal function in nonpregnant women.  Inadequate progesterone production by the corpus luteum may indicate luteal phase deficiency (LPD), which is associated with infertility and early miscarriage. Women using oral contraceptives have suppressed progesterone levels. Levels increase sharply during the luteal phase of the menstrual cycle. The level increases from 9 to 32 weeks of pregnancy.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.