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Prolactin : 746
Test CodePROLA or 746
CPT Codes
84146
Instructions
Overnight fasting is preferred.
Transport Container
Specimen:
1 mL serum
Minimum Volume: 0.5 mL
1 mL serum
Minimum Volume: 0.5 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 5 days; Refrigerated: 7 days; Frozen: 28 days
Methodology
Immunoassay
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
Adult Males 2.0-18.0 ng/mL
Adult Females
Non-Pregnant 3.0-30.0 ng/mL
Pregnant 10.0-209.0 ng/mL
Postmenopausal 2.0-20.0 ng/mL
Stages of Puberty (Tanner Stages)
Female Observed Male Observed
Stage I 3.6.12.0 ng/mL ≤10.0 ng/mL
Stage II-III 2.6-18.0 ng/mL ≤6.1 ng/mL
Stage IV-V 3.2-20.0 ng/mL 2.8-11.0 ng/mL
Adult Females
Non-Pregnant 3.0-30.0 ng/mL
Pregnant 10.0-209.0 ng/mL
Postmenopausal 2.0-20.0 ng/mL
Stages of Puberty (Tanner Stages)
Female Observed Male Observed
Stage I 3.6.12.0 ng/mL ≤10.0 ng/mL
Stage II-III 2.6-18.0 ng/mL ≤6.1 ng/mL
Stage IV-V 3.2-20.0 ng/mL 2.8-11.0 ng/mL
Clinical Significance
During pregnancy and postpartum lactation, serum prolactin can increase 10- to 20-fold. Exercise, stress, and sleep also cause transient increases in prolactin levels. Consistently elevated serum prolactin levels (>30 ng/mL), in the absence of pregnancy and postpartum lactation, are indicative of hyperprolactinemia. Hypersecretion of prolactin can be caused by pituitary adenomas, hypothalamic disease, breast or chest wall stimulation, renal failure or hypothyroidism. A number of drugs, including many antidepressants, are also common causes of abnormally elevated prolactin levels. Hyperprolactinemia often results in galactorrhea, amenorrhea, and infertility in females, and in impotence and hypogonadism in males. Renal failure, hypothyroidism, and prolactin-secreting pituitary adenomas are also common causes of abnormally elevated prolactin levels.
Performing Laboratory
med fusion
