Prolactin : 746

Test Code
PROLA or 746

CPT Codes

Overnight fasting is preferred.

Transport Container
1 mL serum
Minimum Volume: 0.5 mL

Transport Temperature
Room temperature.

Specimen Stability
Room temperature: 5 days; Refrigerated: 7 days; Frozen: 28 days


Setup Schedule
Sunday - Saturday

Report Available
1 day

Reference Range
Adult Males            2.0-18.0 ng/mL 
Adult Females   
  Non-Pregnant      3.0-30.0 ng/mL 
  Pregnant              10.0-209.0 ng/mL 
  Postmenopausal   2.0-20.0 ng/mL 

Stages of Puberty (Tanner Stages) 
                         Female Observed      Male Observed 
Stage I     ng/mL            ≤10.0 ng/mL 
Stage II-III         2.6-18.0 ng/mL            ≤6.1 ng/mL 
Stage IV-V        3.2-20.0 ng/mL            2.8-11.0 ng/mL 

Clinical Significance
During pregnancy and postpartum lactation, serum prolactin can increase 10- to 20-fold. Exercise, stress, and sleep also cause transient increases in prolactin levels. Consistently elevated serum prolactin levels (>30 ng/mL), in the absence of pregnancy and postpartum lactation, are indicative of hyperprolactinemia. Hypersecretion of prolactin can be caused by pituitary adenomas, hypothalamic disease, breast or chest wall stimulation, renal failure or hypothyroidism. A number of drugs, including many antidepressants, are also common causes of abnormally elevated prolactin levels. Hyperprolactinemia often results in galactorrhea, amenorrhea, and infertility in females, and in impotence and hypogonadism in males. Renal failure, hypothyroidism, and prolactin-secreting pituitary adenomas are also common causes of abnormally elevated prolactin levels.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.