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Estradiol : 4021
Test CodeESTDC or 4021
Alias/See Also
Estradiol, 17 Beta, IVF Estradiol, 17-Beta-Estradiol, E2 IVF, Estradiol (E2-6 III)
CPT Codes
82670
Instructions
Note: Do not add Estradiol testing to a barrier gel specimen older than 72 hours .Estradiol binds to barrier gel causing decreased values.
Transport Container
Specimen:
1 mL serum
Minimum Volume: 0.5 mL
1 mL serum
Minimum Volume: 0.5 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum stored on barrier gel for more than 72 hours
Methodology
Immunoassay
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
Female
Follicular Phase 19-144 pg/mL
Mid-Cycle 64-357 pg/mL
Luteal Phase 56-214 pg/mL
Postmenopausal ≤31 pg/mL
Male
≤39 pg/mL
Clinical Significance
Measuring the circulating levels of estradiol is important for assessing the ovarian function and monitoring follicular development for assisted reproduction protocols. Estradiol plays an essential role throughout the human menstrual cycle. Elevated estradiol levels in females may also result from primary or secondary ovarian hyperfunction. Very high estradiol levels are found during the induction of ovulation for assisted reproduction therapy or in pregnancy. Decreased estradiol levels in females may result from either lack of ovarian synthesis (primary ovarian hypofunction and menopause) or a lesion in the hypothalamus-pituitary axis (secondary ovarian hypofunction). Elevated estradiol levels in males may be due to increased aromatization of androgens, resulting in gynecomastia.
Performing Laboratory
med fusion
