Hepatitis C Virus RNA Quantitative Real-Time PCR with Reflex to Genotype : 11348

Test Code
HCVQNR or 11348


Alias/See Also
HCV RNA Genotype * HCV Viral RNA Genotype * Hep C Genotype * Hep C RNA Genotype * Hep C Virus Genotype * Hepatitis C Genotype * Hepatitis C RNA Genotype


CPT Codes
87522

Includes
If HCV RNA, Quantitative, Real-Time PCR is > or = 2000 IU/mL, then Hepatitis C Virus RNA Genotype will be performed at an additional charge (CPT code(s): 87902)


Preferred Specimen
2 mL plasma collected in an EDTA (lavender-top) tube


Minimum Volume
0.6 mL


Other Acceptable Specimens
PPT potassium EDTA (white-top) tube or serum


Instructions
Separate plasma from whole blood within 24 hours of collection by centrifugation. Transfer to a transport tube and refrigerate or freeze.
Serum is collected in a serum separator tube or red-top tube (no gel). Transfer to a transport tube and refrigerate or freeze.


Transport Temperature
Refrigerated


Specimen Stability
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Unspun PPT tube; unspun serum separator tube; unspun red-top tube (no gel); received room temperature; gross hemolysis; grossly lipemic; specimens collected using heparin as anticoagulant.


Methodology
Real Time Polymerase Chain Reaction, Sequencing

Setup Schedule
Monday & Wednesday & Friday
Reflex test: Sunday - Saturday


Report Available
1-4 days;  if reflexed: reflex test will report separately in 2-5 days after receipt at performing  laboratory


Reference Range
Not Detected


Clinical Significance
Useful in monitoring response to therapy and/or disease progression. Reportable range is 15 to 100,000,000 IU/mL (1.18-8.00 log IU/mL).
Determination of hepatitis C genotype is often required to select the most appropriate direct acting agent(s) (DAA) for the treatment of hepatitis C. Some DAA's are only effective for the treatment of hepatitis C genotype 1, whereas others may be used for additional genotypes. A concurrent patient HCV viral load of >=2000 IU/mL is required for this test.


Performing Laboratory
med fusion and Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.