Hepatitis C Virus RNA Quantitative Real-Time PCR with Reflex to Genotype : 11348

Test Code

HCVQNR or 11348

Alias/See Also

HCV RNA Genotype * HCV Viral RNA Genotype * Hep C Genotype * Hep C RNA Genotype * Hep C Virus Genotype * Hepatitis C Genotype * Hepatitis C RNA Genotype

CPT Codes
87522

Includes

If HCV RNA, Quantitative, Real-Time PCR is > or = 2000 IU/mL, then Hepatitis C Virus RNA Genotype will be performed at an additional charge (CPT code(s): 87902)

Preferred Specimen

2 mL plasma collected in an EDTA (lavender-top) tube

Minimum Volume

0.6 mL

Other Acceptable Specimens

PPT potassium EDTA (white-top) tube or serum

Instructions

Separate plasma from whole blood within 24 hours of collection by centrifugation. Transfer to a transport tube and refrigerate or freeze.
Serum is collected in a serum separator tube or red-top tube (no gel). Transfer to a transport tube and refrigerate or freeze.

Transport Temperature

Refrigerated

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Unspun PPT tube; unspun serum separator tube; unspun red-top tube (no gel); received room temperature; gross hemolysis; grossly lipemic; specimens collected using heparin as anticoagulant.

Methodology
Real Time Polymerase Chain Reaction, Sequencing

Setup Schedule

Monday & Wednesday & Friday
Reflex test: Sunday - Saturday

Report Available

1-4 days; if reflexed: reflex test will report separately in 2-5 days after receipt at performing laboratory

Reference Range

Not Detected

Clinical Significance

Useful in monitoring response to therapy and/or disease progression. Reportable range is 15 to 100,000,000 IU/mL (1.18-8.00 log IU/mL).
Determination of hepatitis C genotype is often required to select the most appropriate direct acting agent(s) (DAA) for the treatment of hepatitis C. Some DAA's are only effective for the treatment of hepatitis C genotype 1, whereas others may be used for additional genotypes. A concurrent patient HCV viral load of >=2000 IU/mL is required for this test.

Performing Laboratory
med fusion and Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.