Rivaroxaban : 90981

Test Code
RIVBAN or 90981


Alias/See Also
Xarelto


CPT Codes
80299

Instructions
Collect samples 2-4 hours post dose (peak).
 
Collect in a 3.2% sodium citrate (light blue- top) tube.


Transport Container
Centrifuge the light blue top tube and aliquot 1 mL plasma (Minimum 0.5 mL) into a standard transport tube and freeze immediately.


Transport Temperature
Frozen.


Specimen Stability
Room temperature: Unacceptable Refrigerated: Unacceptable Frozen: 28 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Thawed plasma


Methodology
Chromogenic

Setup Schedule
Monday & Wednesday & Friday


Report Available
1-4 days (From receipt at performing laboratory)


Reference Range
Dosage              Peak (steady state) mcg/L     Trough* mcg/L
20 mg qD            182 - 408                                   3 - 153                   
15 mg qD            180 - 408                                   2 - 161
10 mg qD             91 - 196                                    1 - 38              
 * The lower limit of detection for this assay is 30 mcg/L.


Clinical Significance
Rivaroxaban is an oral factor Xa inhibitor that is indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It is also indicated for the treatment, prophylaxis, or the reduction in the risk of reoccurrence of deep vein thrombosis (DVT) or pulmonary embolism (PE). Rivaroxaban does not need to be monitored routinely, however, exceptions may include determination of failure of therapy vs. poor compliance, or potential dose adjustment required for renal or hepatic dysfunction.


Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.