PTH, Intact and Calcium : 8837

Test Code

PTHCAX or 8837

Alias/See Also

Immunoreactive PTH, Sandwich PTH Assay, PTH Whole Molecule, Intact Hormone, Monogram

CPT Codes
83970, 82310

Includes

Panel includes: PTH and calcium.

Instructions

Intact PTH: EDTA Lavender top tube.
AND
Calcium: Serum separator tube or plain red top tube.

Alternative specimen for PTH: Frozen serum.

Transport Container

PTH: Centrifuge the lavender top tube and aliquot 1.5 mL plasma (Min. 1.0 mL) into a standard transport tube and label as PLASMA.

CALCIUM: Centrifuge the serum separator tube and transport; if a plain red, centrifuge and aliquot 1.0 mL serum into a standard transport tube (Min. 0.5 mL) and label as SERUM.

Alternative specimen for PTH: 2 mL (Min. 1 mL) frozen serum aliquot from a SST or plain red top tube. Label as SERUM.

Transport Temperature

EDTA plasma for PTH amd serum for calcium: Refrigerated.
Serum for PTH: Frozen.

Specimen Stability

EDTA Plasma for PTH: Room temperature: 48 hours; Refrigerated: 72 hours; Frozen: 6 months

Serum for PTH: Room temperature: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months

Serum for Calcium: Room temperature: 24 hours; Refrigerated: 7 days; Frozen: Acceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis, Grossly lipemic, Sodium and Lithium Heparin plasma

Methodology
PTH: Immunoassay; Calcium: Spectrophotometry

Setup Schedule

Sunday - Saturday

Report Available

1 day

Reference Range

Parathyroid Hormone, Intact:
<1 Year         7-58 pg/mL
1-7 Years    12-55 pg/mL
8-18 Years 12-71 pg/mL
≥19 Years   14-64 pg/mL

Calcium:

Calcium:

Age Male (mg/dL) Female (mg/dL)

<1 month: 8.4-10.6 8.4-10.6

1-11 months: 8.7-10.5 8.7-10.5

1-3 years: 8.5-10.6 8.5-10.6

4-19 years: 8.9-10.4 8.9-10.4

20-49 years: 8.6-10.3 8.6-10.2

>49 years: 8.6-10.3 8.6-10.4

Interpretive Guide:
                                              Intact PTH                  Calcium
Normal Parathyroid           Normal                           Normal
Hypoparathyroidism          Low or Low Normal      Low
Hyperparathyroidism
Primary                             Normal or High             High
Secondary                         High                                 Normal or Low
Tertiary                              High                                 High
Non-Parathyroid
    Hypercalcemia               Low or Low Normal        High

Clinical Significance

PTH, Intact and Calcium: Together these tests are useful in making the diagnosis of primary hyperparathyroidism, secondary hyperparathyroidism, and a differential diagnosis of hypercalcemia. These tests help in distinguishing hypercalcemia caused by either primary hyperparathyroidism or malignant disease.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.