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Thyroglobulin Antibodies : 267
Test CodeTHYRBX or 267
Alias/See Also
ATG, TGAb
CPT Codes
86800
Instructions
Serum separator tube (SST) or a plain red top tube.
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Transport Container
Centrifuge the serum separator tube and transport; if a plain red top tube, centrifuge and aliquot 1.0 mL serum (Min. 0.5 mL) into a standard transport tube.
Transport Temperature
Room temperature.
Specimen Stability
After separation from cells: Room temperature: 7 days; Refrigerated : 7 days; Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, grossly lipemic
Methodology
Immunoassay
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
< or = 1 IU/mL
Clinical Significance
Thyroglobulin antibodies (TGAb) are often present in patients with autoimmune thyroid disease. Approximately 10% of healthy individuals have TGAb at measurable levels. TGAb can be detected in 30% of patients with Graves’ disease and in 85% of patients with Hashimoto’s thyroiditis. However, elevated levels of autoantibodies to thyroid peroxidase (TPO autoantibody) occur more frequently than high TGAb levels in these diseases. Sensitive TGAb methods are needed to identify patient sera that contains thyroglobulin autoantibodies that may interfere with serum thyroglobulin measurements.
Performing Laboratory
med fusion
