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Erythropoietin : 427
MessageDue to diurnal variation, it is recommended that specimens be collected between 7:30 am and noon.
Test Code
ERPOTX OR 427
Alias/See Also
Epoletin, EPO, Epogen
CPT Codes
82668
Instructions
Serum separator tube (SST) or plain red top tube.
Transport Container
Centrifuge the serum separator tube and transport. If plain red top tube, centrifuge and aliquot 1.0 mL serum (Min. 0.5 mL) into a standard transport tube.
Transport Temperature
Roon temperature.
Specimen Stability
After separation from cells: Room temperature: 10 days, Refrigerated: 18 days; Frozen: 28 days
Methodology
Immunoassay
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
Male (mIU/mL) Female (mIU/mL)
<1 Year Not established Not established
1-3 Years 1.7-17.9 2.1-15.9
4-6 Years 3.5-21.9 2.9-8.5
7-9 Years 1.0-13.5 2.1-8.2
10-12 Years 1.0-14.0 1.1-9.1
13-15 Years 2.2-14.4 3.8-20.5
16-18 Years 1.5-15.2 2.0-14.2
>18 Years 2.6-18.5 2.6-18.5
<1 Year Not established Not established
1-3 Years 1.7-17.9 2.1-15.9
4-6 Years 3.5-21.9 2.9-8.5
7-9 Years 1.0-13.5 2.1-8.2
10-12 Years 1.0-14.0 1.1-9.1
13-15 Years 2.2-14.4 3.8-20.5
16-18 Years 1.5-15.2 2.0-14.2
>18 Years 2.6-18.5 2.6-18.5
Clinical Significance
Elevated levels of serum erythropoietin (EPO) occur in patients with anemias due to increased red cell destruction in hemolytic anemia and also in secondary polycythemias associated with impaired oxygen delivery to the tissues, impaired pulmonary oxygen exchange, abnormal hemoglobins with increased oxygen affinity, constriction of the renal vasculature, and inappropriate EPO secretion caused by certain renal and extrarenal tumors. Normal or depressed levels may occur in anemias due to increased oxygen delivery to tissues, in hypophosphatemia, and in polycythemia vera.
Performing Laboratory
med fusion
