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PSA, Free and Total : 31348
MessageThe specimen should be collected prior to prostatic manipulation, such as digital rectal examination (DRE), prostatic massage, transrectal ultrasound (TRUS) and prostatic biopsy as results may be falsely elevated.
Test Code
PSATFX or 31348
Alias/See Also
Fractionated PSA, Prostate Specific Antigen Free and Total, Free PSA and Total PSA, PSA, PSA Free
CPT Codes
84153, 84154
Includes
Panel includes: Total PSA, Free PSA, and Percent Free PSA.
Instructions
Serum separator tube (SST) or plain red top tube.
Transport Container
Centrifuge the serum separator tube or plain red top tube, and aliquot 2.0 mL serum (Min. 0.6 mL) into a standard transport tube and freeze.
Transport Temperature
Frozen.
Specimen Stability
After separation from cells: Room temperature: 72 hours, Refrigerated: 72 hours; Frozen: 5 months
Methodology
Immunoassay
Setup Schedule
Sunday - Saturday
Report Available
1 day
Limitations
PSA was performed using the Beckman Coulter Immunoassay method. Values obtained from different assay methods cannot be used interchangeably. PSA levels, regardless of value, should not be interpreted as absolute evidence of the presence or absence of disease.
Reference Range
PSA, Total
Male: ≤4.0 ng/mL
Female: Not established
PSA, Free: See Laboratory Report
PSA, % Free
Male: >25 % (calc)
Female: Not established
Male: ≤4.0 ng/mL
Female: Not established
PSA, Free: See Laboratory Report
PSA, % Free
Male: >25 % (calc)
Female: Not established
Clinical Significance
In men over 50 years with total PSA between 4.0 and 10.0 ng/mL, the percent (%) free PSA gives an estimate of the probability of cancer. In these circumstances the measurement of the % free PSA may aid in avoiding unnecessary biopsies.
Elevated levels of Prostate Specific Antigen (PSA) have been associated with benign and malignant prostatic disorders. Studies indicate that in men 50 years or older measurement of PSA is a useful addition to the digital rectal exam in the early detection of prostate cancer.
In addition, PSA decreases to undetectable levels following complete resection of the tumor and may rise again with recurrent disease or persist with residual disease. Thus, PSA levels may be of assistance in the management of prostate cancer patients.
Elevated levels of Prostate Specific Antigen (PSA) have been associated with benign and malignant prostatic disorders. Studies indicate that in men 50 years or older measurement of PSA is a useful addition to the digital rectal exam in the early detection of prostate cancer.
In addition, PSA decreases to undetectable levels following complete resection of the tumor and may rise again with recurrent disease or persist with residual disease. Thus, PSA levels may be of assistance in the management of prostate cancer patients.
Performing Laboratory
med fusion
