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Comprehensive Meningitis/Encephalitis Panel by PCR, CSF : 38799
MessageThis test code is for CSF only. This test code is only orderable as a panel.
Test Code
RMEPCR or 38799
Alias/See Also
Escherichia coli, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitides, Streptococcus agalactiae (GBS), Streptococcus pneumoniae, Cytomegalovirus (CMV), Enterovirus, Herpes simplex virus 1 (HSV-1), Herpes simplex virus 2 (HSV-2), Human herpesvirus 6 (HHV-6), Human Parechovirus, Varicella-zoster virus (VZV), Cryptococcus neoformans/gattii
CPT Codes
87483
Includes
The panel contains bacterial, viral and fungal targets listed below:
Bacterial: Escherichia coli, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitides, Streptococcus agalactiae (GBS), Streptococcus
Viral: Cytomegalovirus (CMV), Enterovirus, Herpes simplex virus 1 (HSV-1), Herpes simplex virus 2 (HSV-2), Human herpesvirus 6 (HHV-6), Human Parechovirus, Varicella-zoster virus (VZV)
Fungal: Cryptococcus neoformans/gattii
Bacterial: Escherichia coli, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitides, Streptococcus agalactiae (GBS), Streptococcus
Viral: Cytomegalovirus (CMV), Enterovirus, Herpes simplex virus 1 (HSV-1), Herpes simplex virus 2 (HSV-2), Human herpesvirus 6 (HHV-6), Human Parechovirus, Varicella-zoster virus (VZV)
Fungal: Cryptococcus neoformans/gattii
Instructions
CSF must be collected via lumbar puncture.
Transport Container
Submit 0.5 mL CSF (Min. 0.3 mL) in a sterile plastic screw capped container or tube. DO NOT centrifuge.
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 1 day; Refrigerated: 7 days; Frozen: Undetermined
Methodology
Multiplex Qualitative Polymerase Chain Reaction (PCR)
Setup Schedule
Monday - Sunday
Report Available
1 day
Limitations
Non-K1 E. coli serotypes and non-encapsulated strains of Neisseria meningitidis are not detected by this assay.
Viral shedding into the CSF often occurs in cases of zoster. VZV may not be the cause of CNS disease in these cases.
This assay does distinguish between latent and active CMV and HHV-6 infections. Detection of these viruses may indicate primary infection, secondary reactivation, or the presence of latent infection.
This test is not intended for use with CSF collected from indwelling medical devices (e.g., CSF shunts)
Viral shedding into the CSF often occurs in cases of zoster. VZV may not be the cause of CNS disease in these cases.
This assay does distinguish between latent and active CMV and HHV-6 infections. Detection of these viruses may indicate primary infection, secondary reactivation, or the presence of latent infection.
This test is not intended for use with CSF collected from indwelling medical devices (e.g., CSF shunts)
Reference Range
Not Detected
Clinical Significance
Central nervous system (CNS) infections are responsible for causing meningitis, encephalitis or meningoencephalitis. Approximately, 15% of cases are fatal and many other cases result in life-long disabilities such as loss of limbs, visual and hearing deficits, seizures, and altered learning and memory. The Comprehensive Meningitis/Encephalitis Panel aids in rapid diagnosis of patients with CNS symptoms. The panel contains bacterial, viral and fungal targets.
Performing Laboratory
med fusion
