Myasthenia Gravis Panel 2 : 10104

Test Code
ACRABR or 10104

Alias/See Also
Acetylcholine Receptor Binding Antibody, Acetylcholine Receptor Blocking Antibody, Acetylcholine Receptor Modulating Antibody

CPT Codes
83519x3

Includes
Acetylcholine Receptor Binding Antibody, Acetylcholine Receptor Blocking Antibody, Acetylcholine Receptor Modulating Antibody

Instructions
Serum separator tube.

Transport Container
Centrifuge serum separator tube and transport, 2 mL serum (Min: 0.7 mL).

Transport Temperature
Refrigerated.

Specimen Stability
Room temperature: 14 days; Refrigerated: 14 days; Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis; Grossly lipemic; Microbially contaminated

Methodology
Radioimmunoassay (RIA), Radiobinding Assay (RBA)

Setup Schedule
Monday & Thursday

Report Available
2-5 days  (From receipt at performing laboratory)

Limitations
Acetylcholine Receptor Modulating Antibody: This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range
Acetylcholine Receptor Binding Antibody:
Negative ≤0.30 nmol/L
Equivocal 0.31-0.49 nmol/L
Positive ≥0.50 nmol/L

Acetylcholine Receptor Blocking Antibody:
<15 % Inhibition

Acetylcholine Receptor Modulating Antibody:
<32 % Inhibition

Clinical Significance
Myasthenia Gravis is a neurological disorder characterized by a decrease in acetylcholine receptors. Patients exhibit skeletal muscle weakness and fatigability. Approximately 80% of patients with Myasthenia Gravis, excluding ocular involvement only, have detectable acetylcholine receptor antibody.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.