T Cell Receptor Gamma Gene Rearrangement with Reflex to T Cell Receptor Beta Chain Gene Rearrangement (T-Cell Clonality Assay) by PCR : 1016804

Message

For tissue specimens, please provide most recent pathology report.

Test Code

MDFCPTCRREFTCB or 1016804

CPT Codes
81342

Includes

If the T Cell Receptor Gamma Chain Gene Rearrangement by PCR is not definitively positive for clonal rearrangement, the T Cell Receptor Beta Chain Gene Rearrangement will be performed at an additional charge (CPT code(s): 81340).

Instructions

Peripheral Blood in a lavender top tube (EDTA) or Bone Marrow in a lavender top tube (EDTA) or Tissue.

Transport Container

Submit 5 mL Blood (Min. 2 mL) or 2 mL Bone Marrow (Min. 0.5 mL): Do not centrifuge. Fresh Tissue: submit in RPMI media. Paraffin embedded Tissue: submit in sterile biohazard plastic bag. Slides: submit in slide holder. Do not submit decalcified tissue specimen.

Transport Temperature

Blood, Bone Marrow, or Fresh Tissue: Refrigerated; Paraffin embedded Tissue: Ambient or on ice pack in summer; Slides: Ambient.

Specimen Stability

Blood or Bone Marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable

Paraffin embedded tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Fresh tissue: Refrigerated: 24 hours; Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Decalcified tissue specimen.

Methodology
Polymerase Chain Reaction (PCR)

Setup Schedule

Tuesday & Friday

Report Available

2-6 days
If reflex, 4-6 days after reflex added

Limitations

The kit used to perform this test is labeled for RESEARCH USE ONLY. Performance characteristics have been determined by med fusion. This test has not been cleared or approved by the U.S. Food and Drug Administration (FDA).

Reference Range

An interpretive report will be provided.

Clinical Significance

This assay is used to identify clonal rearrangements of the T-cell receptor gamma chain gene and the T-cell receptor beta chain gene present in the majority of T cell and certain B cell malignancies.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.