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Porphyrins, Fractionated, Plasma : 5519
Test CodePORPP or 5519
CPT Codes
82542
Includes
Uroporphyrin, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Coproporphyrin, Protoporphyrin, Total Porphyrins
Instructions
Green (no gel) (heparin), lavender (EDTA), or plain red tube. Protect from light (foil wrap tube).
Transport Container
Protect from light during collection, storage, and shipment. Centrifuge and separate plasma or serum from cells. Avoid hemolysis. Transfer 2 mL plasma or serum to an amber transport tube (preferred) or protect the transport tube from light with foil or place in an amber bag. Freeze immediately. (Min: 0.4 mL)
Transport Temperature
Frozen.
Specimen Stability
After separation from cells and light protected: Ambient: 8 hours; Refrigerated: 8 hours; Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Not light -protected, Serum Separator tube (SST).
Methodology
High Performance Liquid Chromatography (HPLC)
Setup Schedule
Sunday & Wednesday
Report Available
5-10 days (From receipt at performing laboratory)
Reference Range
Uroporphyrin ≤0.2 µg/L
Heptacarboxyporphyrin ≤0.2 µg/L
Hexacarboxyporphyrin ≤0.3 µg/L
Pentacarboxyporphyrin ≤0.4 µg/L
Coproporphyrin ≤0.8 µg/L
Protoporphyrin 0.4-4.8 µg/L
Total Porphyrins 1.0-5.6 µg/L
Heptacarboxyporphyrin ≤0.2 µg/L
Hexacarboxyporphyrin ≤0.3 µg/L
Pentacarboxyporphyrin ≤0.4 µg/L
Coproporphyrin ≤0.8 µg/L
Protoporphyrin 0.4-4.8 µg/L
Total Porphyrins 1.0-5.6 µg/L
Clinical Significance
To diagnose certain types of porphyria. To diagnose patients with chronic renal failure who may be suspected of primary or secondary porphyria.
Performing Laboratory
Quest Diagnostics
