Porphyrins, Fractionated, Plasma : 5519

Test Code
PORPP or 5519

CPT Codes

Uroporphyrin, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Coproporphyrin, Protoporphyrin, Total Porphyrins

Green  (no gel) (heparin), lavender (EDTA), or plain red tube. Protect from light (foil wrap tube).

Transport Container
Protect from light during collection, storage, and shipment. Centrifuge and separate plasma or serum from cells. Avoid hemolysis. Transfer 2 mL plasma or serum to an amber transport tube (preferred) or protect the transport tube from light with foil or place in an amber bag. Freeze immediately.  (Min: 0.4 mL)

Transport Temperature

Specimen Stability
After separation from cells and light protected: Ambient: 8 hours; Refrigerated: 8 hours; Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Not light -protected,  Serum Separator tube (SST).

High Performance Liquid Chromatography (HPLC)

Setup Schedule
Sunday & Wednesday

Report Available
5-10 days  (From receipt at performing laboratory)

Reference Range
Uroporphyrin ≤0.2 µg/L
Heptacarboxyporphyrin  ≤0.2 µg/L
Hexacarboxyporphyrin ≤0.3 µg/L
Pentacarboxyporphyrin ≤0.4 µg/L
Coproporphyrin ≤0.8 µg/L
Protoporphyrin 0.4-4.8 µg/L
Total Porphyrins 1.0-5.6 µg/L

Clinical Significance
To diagnose certain types of porphyria. To diagnose patients with chronic renal failure who may be suspected of primary or secondary porphyria.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.