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HIV-1 Coreceptor Tropism, Proviral DNA : 91299
Test CodeHVCORP or 91299
Alias/See Also
CXCR4, R5, CCR5, Trofile™ ,X4, Human Immunodeficiency Virus
CPT Codes
87906
Instructions
Lavender (EDTA) tube.
Transport Container
Submit 2 mL whole blood in EDTA (lavender-top) tube. (Min: 0.6 mL)
Transport Temperature
Refrigerated.
Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 28 days
Methodology
DNA Sequencing, Polymerase Chain Reaction (PCR)
Setup Schedule
Tuesday & Friday
Report Available
4-8 days (From receipt at performing laboratory)
Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range
See Laboratory Report.
Clinical Significance
The use of CCR5 antagonists requires screening for viral tropism to exclude patients harboring X4 or D/M virus. HIV-1 Proviral DNA tropism test is useful for determination of viral tropism in patients with undetectable HIV-1 viral RNA (virologically suppressed).
Performing Laboratory
Quest Diagnostics
