HIV-1 Resistance, Proviral DNA (RTI, PI, Integrase Inhibitors) : 94807

Test Code

HIVPRO or 94807

Alias/See Also

Archived DNA, Cell-associated Viral DNA, Undetected viral load, Resistance Analysis, Archived resistance

CPT Codes
87900, 87901, 87906

Instructions

Lavender (EDTA) tube.

Transport Container

Submit 2 mL whole blood in EDTA (lavender-top) tube. (Min: 0.6 mL)

Transport Temperature

Refrigerated.

Specimen Stability

Room temperature: 7 days; Refrigerated: 7 days; Frozen: 28 days

Methodology
Polymerase Chain Reaction (PCR), Next Generation (ultra-deep) Sequencing

Setup Schedule

Tuesday & Saturday

Report Available

4-5 days (From receipt at performing laboratory)

Limitations

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range

See Laboratory Report.

Clinical Significance

This test utilizes PCR and next generation (ultra-deep) sequencing of proviral DNA to detect drug resistance mutations in the HIV-1 protease, reverse transcriptase and integrase genes. This information will assist clinicians considering a modification of the treatment regimens for virologically suppressed patients or for patients with a low viral load for whom an RNA resistance test was not successful.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.