Liver Fibrosis, FibroTest-ActiTest Panel : 92688

Test Code
LIVFIB or 92688

CPT Codes

Panel includes: Alanine Aminotransferase (ALT); Alpha-2-Macroglobulin; Apolipoprotein A1; Total Bilirubin; Gamma Glutamyl Transferase (GGT); Haptoglobin; Fibrosis Score; Necroinflammat Act Score.

Overnight fasting is preferred.

Serum separator tube(s). Collect suffcient blood in tube(s) to obtain 3.5 mL serum.

Transport Container
Centrifuge serum separator tube(s) as soon as possiible after visible clot formation (usually 15-30 minutes after collection and transport), 3.5 mL (Min: 2 mL)  Transfer serum to an aliquot tube and freeze.

Transport Temperature

Specimen Stability
After separation from cells: Ambient: 24 hours; Refrigerated:72 hours; Frozen: -20 C : 5 days; -70 C: 28 days (Avoid freezing and thawing.)

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Gross lipemia. Patients less than 2 years old. QNS for one or more analytes.

Nephelometry/Spectrophotometry (SP)

Setup Schedule
Monday - Saturday

Report Available
1-4 days (From receipt at performing laboratory)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range
By report.

Clinical Significance
FibroTest and ActiTest permit the non-invasive evaluation of Hepatitis C (or B) individuals for the presence of liver fibrosis and liver inflammation, respectively. The FibroTest and ActiTest scores are calculated based on patient age, gender and concentrations of serum of y-glutamyl transferase (GGT), total bilirubin (TB), a-2 macroglobulin, haptoglobin, apolipoprotein A1 and alanine aminotransferase (ActiTest). Fibrotest and ActiTest Scores, on a scale of 0.0 to 1.0, are assigned a Metavir scale indicating the level of fibrosis or inflammation present.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.