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Liver Fibrosis, FibroTest-ActiTest Panel : 92688
Test CodeLIVFIB or 92688
CPT Codes
81596
Includes
Panel includes: Alanine Aminotransferase (ALT); Alpha-2-Macroglobulin; Apolipoprotein A1; Total Bilirubin; Gamma Glutamyl Transferase (GGT); Haptoglobin; Fibrosis Score; Necroinflammat Act Score.
Instructions
Overnight fasting is preferred.
Serum separator tube(s). Collect suffcient blood in tube(s) to obtain 3.5 mL serum.
Serum separator tube(s). Collect suffcient blood in tube(s) to obtain 3.5 mL serum.
Transport Container
Centrifuge serum separator tube(s) as soon as possiible after visible clot formation (usually 15-30 minutes after collection and transport), 3.5 mL (Min: 2 mL) Transfer serum to an aliquot tube and freeze.
Transport Temperature
Frozen..
Specimen Stability
After separation from cells: Ambient: 24 hours; Refrigerated:72 hours; Frozen: -20 C : 5 days; -70 C: 28 days (Avoid freezing and thawing.)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Gross lipemia. Patients less than 2 years old. QNS for one or more analytes.
Methodology
Nephelometry/Spectrophotometry (SP)
Setup Schedule
Monday - Saturday
Report Available
1-4 days (From receipt at performing laboratory)
Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range
By report.
Clinical Significance
FibroTest and ActiTest permit the non-invasive evaluation of Hepatitis C (or B) individuals for the presence of liver fibrosis and liver inflammation, respectively. The FibroTest and ActiTest scores are calculated based on patient age, gender and concentrations of serum of y-glutamyl transferase (GGT), total bilirubin (TB), a-2 macroglobulin, haptoglobin, apolipoprotein A1 and alanine aminotransferase (ActiTest). Fibrotest and ActiTest Scores, on a scale of 0.0 to 1.0, are assigned a Metavir scale indicating the level of fibrosis or inflammation present.
Performing Laboratory
Quest Diagnostics