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Porphyrins, Fractionation, Quantitative, Random Urine : 36592
Test CodeUPOFRN or 36592
Alias/See Also
Porphyria
CPT Codes
84120
Includes
Panel includes: Coproporphyrin I, Coproporphyrin III, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Uroporphyrin I, Uroporphyrin III, Total Porphyrins
Instructions
Random urine. Protect from light.
Transport Container
Protect from light. Transfer 2 mL aliquot from well mixed random urine to an amber transport tube (preferred) or protect the container from light with foil or place in an amber bag. (Min: 1.5 mL)
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: Unacceptable; Refrigerated: 7 days; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature. Not protected from light. Samples with a pH less than 4.0.
Methodology
High Performance Liquid Chromatography (HPLC)
Setup Schedule
Sunday & Tuesday - Friday
Report Available
5-7 days (From receipt at performing laboratory)
Reference Range
| Effective 9/10/2018 Adult Reference Ranges: Uroporphyrin I: 3.6-21.1 mcg/g creatinine Uroporphyrin III: less than or equal to 5.6 mcg/g creatinine Heptacarboxyporphyrin: less than or equal to 3.4 mcg/g creatinine Hexacarboxyporphyrin: less than or equal to 6.3 mcg/g creatinine Pentacarboxyporphyrin: less than or equal to 4.1 mcg/g creatinine Coproporphyrin I: 6.5-33.2 mcg/g creatinine Coproporphyrin III: 4.8-88.6 mcg/g creatinine Total Porphyrins: 27.0-153.6 mcg/g creatinine |
Clinical Significance
Clinical use is to diagnose porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria.
Performing Laboratory
Quest Diagnostics
