Lactate Dehydrogenase Isoenzymes : 4411

LD-1 and LD-2 are elevated in hemolyzed specimens. LD-3, LD-4, and LD-5 are labile at low temperatures, and are erroneously low in specimens that have been refrigerated or frozen.

Test Code
LDHISO or 4411

Alias/See Also
LD Isoenzymes

CPT Codes
83625, 83615

Panel includes: LD isoenzymes (1-5) and LDH, Total.

Serum separator tube.

Transport Container
Do not refrigerate or freeze. Centrifuge serum separator tube within 1 hour of collection and transport, 2 mL (Min: 1 mL).

Transport Temperature

Specimen Stability
After separation of cells: Ambient: 7 days; Refrigerated: Unacceptable; Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received frozen. Hemolysis.

Spectrophotometry (SP)/Electrophoresis

Setup Schedule
Monday & Wednesday & Friday

Report Available
2-3 days (From receipt at performing laboratory)

Reference Range
By report.

Clinical Significance
Lactate Dehydrogenase (LD) is an enzyme that is present in many different organs and tissues. LD Isoenzymes (LDI) are useful in distinguishing the different isoenzymes expressed differentially in tissues and organs, e.g., cardiac muscle, skeletal muscle, and liver.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.