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Lactate Dehydrogenase Isoenzymes : 4411
MessageLD-1 and LD-2 are elevated in hemolyzed specimens. LD-3, LD-4, and LD-5 are labile at low temperatures, and are erroneously low in specimens that have been refrigerated or frozen.
Test Code
LDHISO or 4411
Alias/See Also
LD Isoenzymes
CPT Codes
83625, 83615
Includes
Panel includes: LD isoenzymes (1-5) and LDH, Total.
Instructions
Serum separator tube.
Transport Container
Do not refrigerate or freeze. Centrifuge serum separator tube within 1 hour of collection and transport, 2 mL (Min: 1 mL).
Transport Temperature
Ambient.
Specimen Stability
After separation of cells: Ambient: 7 days; Refrigerated: Unacceptable; Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received frozen. Hemolysis.
Methodology
Spectrophotometry (SP)/Electrophoresis
Setup Schedule
Monday & Wednesday & Friday
Report Available
2-3 days (From receipt at performing laboratory)
Reference Range
By report.
Clinical Significance
Lactate Dehydrogenase (LD) is an enzyme that is present in many different organs and tissues. LD Isoenzymes (LDI) are useful in distinguishing the different isoenzymes expressed differentially in tissues and organs, e.g., cardiac muscle, skeletal muscle, and liver.
Performing Laboratory
Quest Diagnostics
