MYB-6q23 deletion by FISH : 1002648

MDFCPCMYB or 1002648

6q-; deletion 6q

Bone Marrow aspirate in a green top sodium heparin tube (2-3 mL) or Peripheral Blood in a green top sodium heparin tube (2-10 mL).

Blood or Bone Marrow: Do not centrifuge.

Blood or Bone Marrow: Ambient temperature within 24 hours. Specimen can be refrigerated if not transported immediately. Do not freeze. Protect from heat with a cold pack.

Blood and Bone Marrow: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable

Monday - Friday

Up to 7 days

Laboratory test results should always be considered in the context of clinical observations. This test was developed and its performance characteristics determined by med fusion. It has not been cleared or approved by the U.S. Food and Drug Administration
(FDA). The FDA has determined that such clearance or approval is not necessary. This test is used for clinical purposes. It should not be regarded as investigational for research. This laboratory is certified under the Clinical Laboratory Improvement Amendments
of 1988 (CLIA) as qualified to perform high complexity clinical laboratory testing.

An interpretive report will be provided.

Del(6q) has been found in a variety of B cell neoplasms, mostly in combination with other chromosome changes. Three regions of minimal critical deletions of 6q have been delineated and the existence of a tumor suppressor gene(s) on 6q, involved in the pathogenesis of lymphoma, has been proposed. Del(6q) as the sole abnormality or together with additional chromosome changes has been reported in 42-63% of patients with lymphoplasmacytic lymphoma.