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Cryptococcus Antigen Screen, CSF : 1000186
Test CodeCFCRYT or 1000186
Alias/See Also
Cryptococcus Ag Screen, CSF
CPT Codes
86403
Includes
If screen is positive, Cryptococcus Antigen titer will be performed at an additional charge (CPT code(s): 86406).
Instructions
Spinal fluid:
1. Collect spinal fluid according to standard procedures.
2. Place 1 mL CSF into a sterile tube.
3. Refrigerate and submit at 4 C. (may be submitted ambient if received in the laboratory within 24 hours)
1. Collect spinal fluid according to standard procedures.
2. Place 1 mL CSF into a sterile tube.
3. Refrigerate and submit at 4 C. (may be submitted ambient if received in the laboratory within 24 hours)
Transport Container
Submit 1 mL CSF in a sterile screw capped tube.
Transport Temperature
Refrigerated. May be submitted at Ambient temperature if the specimen is received in the laboratory within 24 hours.
Specimen Stability
Ambient: 24 hours; Refrigerated: 7 days; Frozen: 7 days
Methodology
Immunochromatographic lateral flow assay
Setup Schedule
Sunday - Saturday
Report Available
1-2 days
Reference Range
Negative
Clinical Significance
The cryptococcal antigen lateral flow assy is an immunochomatographic test system for the detection of the polysaccharide antigens of Cryptococus neoformans and Cryptococcusgattii in serum and cerebral spinal fluid (CSF). It uses a dipstick sandwich technique with specimen wicking to detect cryptococcal antigen using highly specific monoclonal antibodies. Cryptococcosis is cause by both C. neoformans and C. gattii. Individuals with impaired cell mediated immunity are at greatest risk of infection. Cryptococcosis is one of the most common opportunistic infections in AIDS patients. Detection of cryptococcal antigen in serum and CSF has been extensively utilized with very high sensitivity and specificity.
Performing Laboratory
med fusion
