Anti-Neutrophil Cytoplasmic Antibodies (ANCA) with reflex to MPO Antibody and PR3 Antibody : 1015888

Test Code

ANCAR or 1015888

Alias/See Also

ANCA; cANCA; pANCA; Antineutrophil Cytoplasmic Antibody; Wegners Disease; Churg-Strauss Syndrome; Neutrophil Cytoplasmic Antibodies; MPO; PR3

CPT Codes
86036

Includes

If the screen is positive, ANCA titer and pattern are performed at an additional charge (CPT code(s): 86037), Myeloperoxidase Antibody (test code MPOAB, 100638) (CPT code(s): 86021) Serine Protease 3 Antibody (test code PR3, 100736) (CPT code(s): 86021).

Instructions

Serum separator tube (gold top preferred) or a plain red top tube.

Transport Container

Centrifuge the serum separator tube and transport; if a plain red top tube, centrifuge and aliquot serum (Min. 0.5 mL) into a standard transport tube.

Transport Temperature

Refrigerated.

Specimen Stability

Refrigerated: 48 hours; Frozen: Acceptable for longer periods

Methodology
Immunofluorescence Assay (IFA) and Multiplex flow Immunoassay

Setup Schedule

Monday & Wednesday & Friday

Report Available

1-4 days

Reference Range

ANCA: Negative
MPO: Negative
PR3: Negative

Clinical Significance

Testing for anti-neutrophil cytoplasmic antibodies (ANCA) is useful in the diagnosis of vasculitides such as Wegener’s granulomatosis, polyarteritis nodosa and Churg-Strauss syndrome. These autoantibodies are frequently directed toward enzymes within the neutrophil primary granules such as myeloperoxidase (MPO) and serine proteinase 3 (PR3).

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.