Inflammatory Bowel Disease Differentiation Panel : 16503

Test Code

IBDPAN or 16503

Alias/See Also

IBD, UC, Ulecrative Colitis, CD, Crohn's Disease

CPT Codes
86021x2, 86036, 86671x2 with reflexes

Includes

Panel includes ANCA Screen with reflex to titer, Myeloperoxidase Antibody (MPO), Proteinase 3 Anitbody, Saccharomyces cerevisiase Antibodies (ASCA) IgG and IgA. If ANCA Screen is positive, C-ANCA Titer and/or P-ANCA Titer and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed). (If reflex, may include: non-orderables 16503-4 APANCT, and/or 16503-3 CANCAT , and/or 16503-2 PANCAT)

Instructions

Serum separator tube.

Transport Container

Centrifuge serum separator tube and transport 2.0 mL serum. (Min: 1.4 mL)

Transport Temperature

Refrigerated.

Specimen Stability

After separation from cells: Ambient: 7 days; Refrigerated: 14 days; Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis. Lipemic specimens.

Methodology
Immunoassay

Setup Schedule

Monday - Saturday

Report Available

3-5 days (From receipt at performing laboratory)

Reference Range

ANCA Screen Negative
P-ANCA Titer less than 1:20
C-ANCA Titer less than 1:20
Atypical P-ANCA Titer less than 1:20

Myeloperoxidase Antibody
less than 1.0 AI No antibody detected
greated than or equal to 1.0 AI Antibody detected

Proteinase-3 Antibody
less than 1.0 AI No antibody detected
greater than or equal to 1.0 AI Antibody detected

Saccharomyces cerevisiae (IgG)
less than or equalt to 20 U Negative
20.1-29.9 U Equivocal
greatter than or equal to 30 U Positive

Saccharomyces cerevisiae (IgA)
less tha or equal to 20 U Negative
20.1-24.9 U Equivocal
greater than or equal to 25 U Positive

Clinical Significance

These tests are intended to aid in the diagnosis of Crohn's Disease. A positive P-ANCA aids in the differentiation of patients with ulcerative colitis.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.