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Chromosome Analysis, Non-Leukemic Mosiacism : 1004385
MessagePlease submit completed Postnatal Clinical Information Form. Contact med fusion Client Services for form.
Test Code
MDFCPCHRMOS or 1004385
Alias/See Also
Karyotype; chroms; Karyogram
CPT Codes
88230, 88263, 88280, 88285
Instructions
Peripheral Blood in a green top sodium heparin tube (2-10 mL). For children under 1 year of age, 1-2 mL blood will be sufficient.
Transport Container
Submit whole blood. Do not centrifuge.
Transport Temperature
Ambient temperature within 24 hours. Do not freeze.
Specimen Stability
Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Methodology
Karyotyping
Setup Schedule
Sunday - Saturday
Report Available
Up to 10 days
Limitations
Laboratory test results should always be considered in the context of clinical observations. This test was developed and its performance characteristics determined by med fusion. It has not been cleared or approved by the U.S. Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary. This test is used for clinical purposes. It should not be regarded as investigational for research. This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) as qualified to perform high complexity clinical laboratory testing.
Reference Range
An interpretive report will be provided.
Clinical Significance
Chromosome abnormalities are associated with birth defects and congenital conditions. These abnormalities can be numerical or structural changes in chromosomes. There are several clinical situations which warrant chromosome analysis such as problems with early growth and development, still birth and neonatal death, fertility issues or identifying a chromosomal abnormality associated with a family history. Chromosome analysis by karyotyping can assist in making a diagnosis in a wide range of suspected congenital issues. Chromosome analysis, Mosaicism testing can rule out some of the most common cytogenetic abnormalities:
1) Trisomies for chromosomes 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome);
2) Turner syndrome (45,X) and Klinefelter syndrome (47,XXY) and other abnormalities of the sex chromosomes;
3) Structural chromosomal rearrangements; and
4) Mosaicism.
1) Trisomies for chromosomes 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome);
2) Turner syndrome (45,X) and Klinefelter syndrome (47,XXY) and other abnormalities of the sex chromosomes;
3) Structural chromosomal rearrangements; and
4) Mosaicism.
Performing Laboratory
med fusion