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TSI (Thyroid Stimulating Immunoglobulin) : 30551
Test CodeTSIGG or 30551
Alias/See Also
Long Acting Thyroid Stimulator, (LATS),TSIG,Thyretain (TM), Thyroid Stimulating Antibody
CPT Codes
84445
Instructions
Serum separator tube.
Transport Container
Centrifuge the serum separator tube and transport 1 mL serum. (Min: 0.2)
Transport Temperature
Refrigerated.
Specimen Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 21 days; Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Grossly lipemic Grossly icteric, Plasma.
Methodology
In Vitro Bioassay
Setup Schedule
Monday - Saturday
Report Available
2-3 days (From receipt at performing laboratory)
Reference Range
less than 140% Baseline
Clinical Significance
Graves' disease is a classic form of hyperthyroid disease, affecting approximately 0.4% of the population of the United States. It is caused by IgG immunoglobulins, collectively known as thyroid stimulating immunoglobulins (TSI). Patients who are candidates for antithyroid drug therapy may not respond to this treatment when TSI levels are markedly elevated. The determination of TSI can also assist in predicting hyperthyroidism in neonates, due to placental transmission of the immunoglobulins from a mother with hyperthyroidism.
Performing Laboratory
Quest Diagnostics